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KMID : 0604620010080010029
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Dongguk Journal of Medicine
2001 Volume.8 No. 1 p.29 ~ p.44
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Microtubules and Kinesin Superfamily Proteins and Organelle Transport
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Seog Dae-Hyun
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Abstract
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The neuron sort proteins and lipids, after their synthesis, to various destinations at appropriate velocities in membranous organelles and protein complexes. Intracellular transport is thus fundamental to cellular morphogenesis and functioning. Microtubules serve as a rail on which motor proteins, such as kinesin and dynein superfamily proteins, convey their cargoes. This review focuses on the kinesin superfamily proteins and the molecular mechanism of organelle transport in neuronal cells.
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